Found 35 matching trials
Dabrafenib, Trametinib, and Spartalizumab for the Treatment of BRAF V600E or V600K Mutation Positive Stage IIIB/C/D Melanoma PHASE2 This phase II trial studies how well dabrafenib, trametinib, and spartalizu...
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M D Anderson Cancer Center
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Dabrafenib and Trametinib Before and After Surgery in Treating Patients With Stage IIIB-C Melanoma With BRAF V600 Mutation PHASE2 This is a single arm phase II trial focused on how dabrafenib and trametini...
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Active Not Recruiting
Location
M D Anderson Cancer Center
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Dabrafenib and Trametinib in People With BRAF V600E Mutation Positive Lesions in Erdheim Chester Disease PHASE2 Erdheim-Chester Diseases (ECD) is a very rare non-Langerhans cell histiocyt...
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National Institutes of Health Clinical Center, 9000 Rockville Pike
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Melanoma Metastasized to the Brain and Steroids PHASE2 This clinical trial is to clarify whether treatment with a checkpoint inhib...
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Herlev Universityhospital
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Dabrafenib/Trametinib, BRAF or BRAF AND MEK Pre-op With BRAF and MEK Post-op, Phase IIB, Melanoma With Brain Mets,Biomarkers and Metabolites PHASE2 This is a global, multi-centre, open-label, study of GSK2118436 conducted i...
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GSK Investigational Site
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Dabrafenib and Trametinib Combination as a Neoadjuvant Strategy in BRAF-positive Anaplastic Thyroid Cancer PHASE2 The aim of the study was to evaluate the effectiveness of combination thera...
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Saint-Petersburg State University (SPSU) N.I.Pirogov Clinic of High Medical Technologies
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Combining Talimogene Laherparepvec With BRAF and MEK Inhibitors in BRAF Mutated Advanced Melanoma PHASE1 The purpose of the study is to determine safety and tolerability of the com...
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West Cancer Center
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Study of the Rechallenge Concept in Patients With BRAF-positive Anaplastic Thyroid Cancer After Progression on Anti-BRAF Therapy PHASE2 This pilot phase 2 study evaluates the effectiveness and safety of the Rech...
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Saint Petersburg State University Hospital
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Dabrafenib With Trametinib in the Adjuvant Treatment of High-risk BRAF V600 Mutation-positive Melanoma (COMBI-AD). PHASE3 This was a two-arm, randomized, double-blind Phase III study of dabrafenib ...
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Novartis Investigative Site
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Testing the Addition of the Anti-cancer Drug, Tazemetostat, to the Usual Treatment (Dabrafenib and Trametinib) for Metastatic Melanoma That Has Progressed on the Usual Treatment PHASE1 This phase I/II trial investigates the best dose, possible benefits and/or ...
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Active Not Recruiting
Location
UM Sylvester Comprehensive Cancer Center at Aventura
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